4.9/5 · Based on 20,000+ verified reviews

Two Paths to Sustainable Weight Loss

Physician-Prescribed

Shipped Discreetly

No Insurance Needed

Personalized care, proven treatments, and a plan built around your goals.

Starting at

$169/mo

$299

+ $50 off your first month *3 month program

Made in the USA

HIPAA Compliant

LegitScript Certified

Tirzepatide + B12

Up to 20% loss*

Compounded GLP-1

Up to 15% loss*

Two Treatments · One Mission

Pick the Protocol Built for You

Both are physician-prescribed. Both are compounded in US-licensed pharmacies. The right one for you depends on how aggressive you want to be and your provider will help you choose during your consultation.

Most Popular

Compounded Semaglutide

+ B12 · GLP-1 Agonist

Semaglutide turns down the volume on hunger and food noise, slows digestion, and stabilizes blood sugar so you eat less without thinking about it. Best for steady, sustainable loss.

15%

Mean weight loss at 68 weeks*

Weekly self-injection

Suppresses appetite & ends food cravings within 7–14 days

Improves insulin sensitivity & blood sugar control

B12 added for sustained energy through the dose

Most Popular

Compounded Semaglutide

+ B12 · GLP-1 Agonist

Semaglutide turns down the volume on hunger and food noise, slows digestion, and stabilizes blood sugar so you eat less without thinking about it. Best for steady, sustainable loss.

15%

Mean weight loss at 68 weeks*

Weekly self-injection

Suppresses appetite & ends food cravings within 7–14 days

Improves insulin sensitivity & blood sugar control

B12 added for sustained energy through the dose

Most Popular

Compounded Semaglutide

+ B12 · GLP-1 Agonist

Semaglutide turns down the volume on hunger and food noise, slows digestion, and stabilizes blood sugar so you eat less without thinking about it. Best for steady, sustainable loss.

15%

Mean weight loss at 68 weeks*

Weekly self-injection

Suppresses appetite & ends food cravings within 7–14 days

Improves insulin sensitivity & blood sugar control

B12 added for sustained energy through the dose

Fastest Results

Compounded Tirzepatide

+ B12 · Dual GLP-1 / GIP Agonist

The next-generation, dual-action peptide. Tirzepatide hits both GLP-1 and GIP receptors for faster appetite suppression, deeper fat loss, and better metabolic results than GLP-1 alone in head-to-head trials.

20%

Mean weight loss at 68 weeks*

Weekly self-injection

Dual-receptor action — faster, deeper fat loss vs. GLP-1 alone

Resets how your body stores fat & uses glucose

B12 added to reduce fatigue during rapid loss phase

Fastest Results

Compounded Tirzepatide

+ B12 · Dual GLP-1 / GIP Agonist

The next-generation, dual-action peptide. Tirzepatide hits both GLP-1 and GIP receptors for faster appetite suppression, deeper fat loss, and better metabolic results than GLP-1 alone in head-to-head trials.

20%

Mean weight loss at 68 weeks*

Weekly self-injection

Dual-receptor action — faster, deeper fat loss vs. GLP-1 alone

Resets how your body stores fat & uses glucose

B12 added to reduce fatigue during rapid loss phase

Fastest Results

Compounded Tirzepatide

+ B12 · Dual GLP-1 / GIP Agonist

The next-generation, dual-action peptide. Tirzepatide hits both GLP-1 and GIP receptors for faster appetite suppression, deeper fat loss, and better metabolic results than GLP-1 alone in head-to-head trials.

20%

Mean weight loss at 68 weeks*

Weekly self-injection

Dual-receptor action — faster, deeper fat loss vs. GLP-1 alone

Resets how your body stores fat & uses glucose

B12 added to reduce fatigue during rapid loss phase

Get Started In 3 Simple Steps

Step 1

~5 minutes

Online Physician Consultation

Answer a few health questions and consult with one of our licensed providers online. No awkward visits, no waiting rooms.

Step 1

~5 minutes

Online Physician Consultation

Answer a few health questions and consult with one of our licensed providers online. No awkward visits, no waiting rooms.

Step 2

~24–48 hours

Prescription Approved

Once approved, your prescription is processed, and your medication is discreetly shipped directly to your door.

Step 2

~24–48 hours

Prescription Approved

Once approved, your prescription is processed, and your medication is discreetly shipped directly to your door.

Step 3

Week 1 onward

Feel The Difference

Start your treatment with physician-guided support and feel the difference with weight loss medication.

Step 3

Week 1 onward

Feel The Difference

Start your treatment with physician-guided support and feel the difference with weight loss medication.

Semaglutide vs Tirzepatide

The Honest Side-By-Side

Tirzepatide is newer and stronger. Semaglutide has a longer track record and is gentler on the system. Here's exactly how they stack up.

Semaglutide
Tirzepatide
How it works

GLP-1 receptor agonist

Dual GLP-1 + GIP agonist

Average weight loss*

~15% at 68 weeks

~20% at 72 weeks

Speed of results

Slower, steady progress

Faster, more aggressive

Dosing

1× weekly injection

1× weekly injection

Best for

First-timers, gentler onboarding

Maximum results, stalled plateaus

Starting price

$169/mo

$249/mo

Testimonials

What 20,000+ Patients Say After the First Month

Verified Trustpilot reviews. No filters. No paid actors. Just guys who finally stopped fighting their weight and started winning.

  • Down 18 Lbs. Smooth and Easy.

    "I was skeptical at first about using GLP-1 for weight loss, but PeterMD made the process so smooth and easy. After starting the treatment, I noticed a difference within weeks. My appetite decreased significantly, and I've already lost 18 pounds. The appointments are super convenient, and I love that I can manage my weight loss journey without leaving home. I feel so much more confident and healthier now!"

    Jordan B.

    Verified Review

    18 lbs · 6 weeks

  • Down 30 Lbs. Finally Something That Works.

    "I've struggled with weight for most of my life, and nothing seemed to work long-term until I tried semaglutide through PeterMD. In just a few months, I've lost 30 pounds, and the best part is that it feels sustainable. The medication curbs my appetite, and I don't feel like I'm constantly battling cravings anymore. The telehealth system is a huge plus — I get all the support I need without having to make in-person appointments."

    Tony Chastain

    Verified Review

    30 lbs · 3 months

  • Down 21 Lbs. Reasonably Priced and It Works.

    "I absolutely love Peter MD for my weight loss journey. Very reasonably priced. I went from 230 lbs in January 2025 to 209 lbs in August 2025. Also, it helps with controlling appetite. Love it, highly recommended. Thanks Peter MD."

    Audie M.

    Verified Review

    21 lbs · 7 months

  • Down 44 Lbs. Efficient and Helpful.

    "A valued doctor using PeterMD for GLP-1 weight loss referred me. PeterMD has been fabulous to deal with, very efficient and helpful. I have been taking GLP-1/Tirzepatide since March 16, 2025, and have comfortably lost 44 lbs up until now. I highly recommend both the company and the medication."

    Alexandra K.

    Verified Review

    44 lbs · 14 months

  • Down 18 Lbs. Smooth and Easy.

    "I was skeptical at first about using GLP-1 for weight loss, but PeterMD made the process so smooth and easy. After starting the treatment, I noticed a difference within weeks. My appetite decreased significantly, and I've already lost 18 pounds. The appointments are super convenient, and I love that I can manage my weight loss journey without leaving home. I feel so much more confident and healthier now!"

    Jordan B.

    Verified Review

    18 lbs · 6 weeks

  • Down 30 Lbs. Finally Something That Works.

    "I've struggled with weight for most of my life, and nothing seemed to work long-term until I tried semaglutide through PeterMD. In just a few months, I've lost 30 pounds, and the best part is that it feels sustainable. The medication curbs my appetite, and I don't feel like I'm constantly battling cravings anymore. The telehealth system is a huge plus — I get all the support I need without having to make in-person appointments."

    Tony Chastain

    Verified Review

    30 lbs · 3 months

  • Down 21 Lbs. Reasonably Priced and It Works.

    "I absolutely love Peter MD for my weight loss journey. Very reasonably priced. I went from 230 lbs in January 2025 to 209 lbs in August 2025. Also, it helps with controlling appetite. Love it, highly recommended. Thanks Peter MD."

    Audie M.

    Verified Review

    21 lbs · 7 months

  • Down 44 Lbs. Efficient and Helpful.

    "A valued doctor using PeterMD for GLP-1 weight loss referred me. PeterMD has been fabulous to deal with, very efficient and helpful. I have been taking GLP-1/Tirzepatide since March 16, 2025, and have comfortably lost 44 lbs up until now. I highly recommend both the company and the medication."

    Alexandra K.

    Verified Review

    44 lbs · 14 months

  • Down 18 Lbs. Smooth and Easy.

    "I was skeptical at first about using GLP-1 for weight loss, but PeterMD made the process so smooth and easy. After starting the treatment, I noticed a difference within weeks. My appetite decreased significantly, and I've already lost 18 pounds. The appointments are super convenient, and I love that I can manage my weight loss journey without leaving home. I feel so much more confident and healthier now!"

    Jordan B.

    Verified Review

    18 lbs · 6 weeks

  • Down 30 Lbs. Finally Something That Works.

    "I've struggled with weight for most of my life, and nothing seemed to work long-term until I tried semaglutide through PeterMD. In just a few months, I've lost 30 pounds, and the best part is that it feels sustainable. The medication curbs my appetite, and I don't feel like I'm constantly battling cravings anymore. The telehealth system is a huge plus — I get all the support I need without having to make in-person appointments."

    Tony Chastain

    Verified Review

    30 lbs · 3 months

  • Down 21 Lbs. Reasonably Priced and It Works.

    "I absolutely love Peter MD for my weight loss journey. Very reasonably priced. I went from 230 lbs in January 2025 to 209 lbs in August 2025. Also, it helps with controlling appetite. Love it, highly recommended. Thanks Peter MD."

    Audie M.

    Verified Review

    21 lbs · 7 months

  • Down 44 Lbs. Efficient and Helpful.

    "A valued doctor using PeterMD for GLP-1 weight loss referred me. PeterMD has been fabulous to deal with, very efficient and helpful. I have been taking GLP-1/Tirzepatide since March 16, 2025, and have comfortably lost 44 lbs up until now. I highly recommend both the company and the medication."

    Alexandra K.

    Verified Review

    44 lbs · 14 months

  • Down 18 Lbs. Smooth and Easy.

    "I was skeptical at first about using GLP-1 for weight loss, but PeterMD made the process so smooth and easy. After starting the treatment, I noticed a difference within weeks. My appetite decreased significantly, and I've already lost 18 pounds. The appointments are super convenient, and I love that I can manage my weight loss journey without leaving home. I feel so much more confident and healthier now!"

    Jordan B.

    Verified Review

    18 lbs · 6 weeks

  • Down 30 Lbs. Finally Something That Works.

    "I've struggled with weight for most of my life, and nothing seemed to work long-term until I tried semaglutide through PeterMD. In just a few months, I've lost 30 pounds, and the best part is that it feels sustainable. The medication curbs my appetite, and I don't feel like I'm constantly battling cravings anymore. The telehealth system is a huge plus — I get all the support I need without having to make in-person appointments."

    Tony Chastain

    Verified Review

    30 lbs · 3 months

  • Down 21 Lbs. Reasonably Priced and It Works.

    "I absolutely love Peter MD for my weight loss journey. Very reasonably priced. I went from 230 lbs in January 2025 to 209 lbs in August 2025. Also, it helps with controlling appetite. Love it, highly recommended. Thanks Peter MD."

    Audie M.

    Verified Review

    21 lbs · 7 months

  • Down 44 Lbs. Efficient and Helpful.

    "A valued doctor using PeterMD for GLP-1 weight loss referred me. PeterMD has been fabulous to deal with, very efficient and helpful. I have been taking GLP-1/Tirzepatide since March 16, 2025, and have comfortably lost 44 lbs up until now. I highly recommend both the company and the medication."

    Alexandra K.

    Verified Review

    44 lbs · 14 months

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FAQs

Straight Answers to Fair Questions

If you don't see your question here, our care team responds in under 4 hours every day, including weekends.

What is Semaglutide?

Semaglutide is an FDA-approved medication that regulates appetite and metabolism, helping you achieve significant, long-term weight loss.

What is Semaglutide?

Semaglutide is an FDA-approved medication that regulates appetite and metabolism, helping you achieve significant, long-term weight loss.

Do I need to visit a doctor in person?

No, PeterMD offers telemedicine visits with licensed physicians, saving you time and hassle.

Do I need to visit a doctor in person?

No, PeterMD offers telemedicine visits with licensed physicians, saving you time and hassle.

How quickly will I see results?

Most users begin noticing results within the first few weeks, with the potential to lose up to 1-2 pounds per week.

How quickly will I see results?

Most users begin noticing results within the first few weeks, with the potential to lose up to 1-2 pounds per week.

Is Semaglutide safe?

Yes, semaglutide is FDA-approved and our physicians monitor your progress to ensure safety and effectiveness.

Is Semaglutide safe?

Yes, semaglutide is FDA-approved and our physicians monitor your progress to ensure safety and effectiveness.

How is Tirzepatide different from GLP1 or Tesamorelin?

Tirzepatide is the only treatment that activates both GIP and GLP-1 receptors. This allows it to reduce appetite and improve insulin sensitivity more effectively than GLP1. Unlike Tesamorelin, it doesn’t stimulate growth hormone or specifically target visceral fat.

How is Tirzepatide different from GLP1 or Tesamorelin?

Tirzepatide is the only treatment that activates both GIP and GLP-1 receptors. This allows it to reduce appetite and improve insulin sensitivity more effectively than GLP1. Unlike Tesamorelin, it doesn’t stimulate growth hormone or specifically target visceral fat.

Is Tirzepatide only for people with diabetes?

No. While Tirzepatide was originally developed for type 2 diabetes, it's also shown powerful weight loss effects in non-diabetic individuals. Many patients using Tirzepatide for weight management do not have diabetes. It regulates blood sugar and reduces appetite, supporting fat loss regardless of your diagnosis. Your provider will determine if it's a good fit based on your overall health and goals.

Is Tirzepatide only for people with diabetes?

No. While Tirzepatide was originally developed for type 2 diabetes, it's also shown powerful weight loss effects in non-diabetic individuals. Many patients using Tirzepatide for weight management do not have diabetes. It regulates blood sugar and reduces appetite, supporting fat loss regardless of your diagnosis. Your provider will determine if it's a good fit based on your overall health and goals.

How much weight can I lose?

Clinical trials showed that recipients using weekly doses experienced a mean weight loss of up to 20% at 72 weeks.

How much weight can I lose?

Clinical trials showed that recipients using weekly doses experienced a mean weight loss of up to 20% at 72 weeks.

Is Tirzepatide safe?

Tirzepatide is FDA-approved and prescribed by licensed doctors. Although rare, side effects are similar to other GLP-1s: nausea, constipation, or fatigue, especially in early stages.

Is Tirzepatide safe?

Tirzepatide is FDA-approved and prescribed by licensed doctors. Although rare, side effects are similar to other GLP-1s: nausea, constipation, or fatigue, especially in early stages.

Launch Offer · $100 Off

Stop fighting your weight. Start outsmarting it.

Stop fighting your weight. Start outsmarting it.

Take the 5-minute consultation. If you qualify, your medication ships in 5 days. If you don't, you pay nothing and we'll tell you what to do instead.

Made in the USA

HIPAA Compliant

LegitScript Certified

Tirzepatide is a prescription medication. Use only under the supervision of a licensed physician. Individual results vary. Not for use in pregnancy.

Tirzepatide is a prescription medication. Use only under the supervision of a licensed physician. Individual results vary. Not for use in pregnancy.

© 2026 PeterMD

Tirzepatide is a prescription medication. Use only under the supervision of a licensed physician. Individual results vary. Not for use in pregnancy.